Statistics Applied to Clinical Trials

• Main Authors: Cleophas, Ton J. (Author), Zwinderman, Aeilko H. (Author), Cleophas, Toine F. (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Dordrecht : Springer Netherlands, 2006.
• Subjects: Statistics.; Statistics for Life Sciences, Medicine, Health Sciences.

In 1948 the first randomized controlled trial was published by the English Medical Research Council in the British Medical Journal. Until then, observations had been uncontrolled. Initially, trials frequently did not confirm hypotheses to be tested. This phenomenon was attributed to low sensitivity...