ARF Family GTPases

• Main Author: Kahn, Richard A. (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Dordrecht : Springer Netherlands, 2003.
• Series: Proteins and Cell Regulation ; 1
• Subjects: Life sciences.; Biochemistry.; Evolutionary biology.; Life Sciences.; Biochemistry, general.; Evolutionary Biology.

For the first time experts in the area of signalling research with a focus on the ARF family have contributed to the production of a title devoted to ARF biology. A comprehensive phylogenetic analysis of the ARF family, tables of the ARF GEFs and ARF GAPs, and more than a dozen chapters describing t...

Table of Contents:

• The Arf Family Tree
• The GDP/GTP Cycle of Arf Proteins
• Arf and Phospholipids
• The Sec7 Family of Arf Guanine Nucleotide Exchange Factors
• Large Arf GEFs of the Golgi Complex
• BIG1 and BIG2: Brefeldin A-Inhibited Exchange Factors for Arfs
• Arf GTPase-Activating Protein 1
• GIT Proteins: Arf Gaps and Signaling Scaffolds
• Paxillin-Associated Arf GAPs
• Activation of Cholera Toxin and E. Coli Heat-Labile Enterotoxin (LT) by Arf
• Phospholipase D, Arfaptins and Arfophilin
• Coat Proteins
• Heterotetrameric Coat Protein-Arf Interactions
• Arf6
• A Role for Arf6 in G Protein-coupled Receptor Desensitization
• Arf-Like Proteins.