RADIOIONIDATION REACTIONS FOR RADIO PHARMACEUTICALS

Molecules of biological interest for in-vivo and in-vitro research or diagnostics of metabolic functions and of neuro-transmission are very often labeled with iodine. Based on state-of-the-art research, this compendium describes the major production routes of the six most relevant iodine radio isoto...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: COENEN, HEINZ H. (Επιμελητής έκδοσης), MERTENS, JOHN (Επιμελητής έκδοσης), MAZIEÈRE, BERNARD (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Dordrecht : Springer Netherlands, 2006.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
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020 |a 9781402045615  |9 978-1-4020-4561-5 
024 7 |a 10.1007/1-4020-4561-1  |2 doi 
040 |d GrThAP 
050 4 |a QD415-436 
072 7 |a PNN  |2 bicssc 
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082 0 4 |a 547  |2 23 
245 1 0 |a RADIOIONIDATION REACTIONS FOR RADIO PHARMACEUTICALS  |h [electronic resource] /  |c edited by HEINZ H. COENEN, JOHN MERTENS, BERNARD MAZIEÈRE. 
246 3 |a With contributions by numerous experts 
264 1 |a Dordrecht :  |b Springer Netherlands,  |c 2006. 
300 |a XI, 101 p.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
505 0 |a Iodine Radionuclides -- Iodinated Radiopharmaceuticals -- Methods of Radioiodination -- Iodinated Radiopharmaceuticals -- Expert System -- Guidelines for Radioiodination. 
520 |a Molecules of biological interest for in-vivo and in-vitro research or diagnostics of metabolic functions and of neuro-transmission are very often labeled with iodine. Based on state-of-the-art research, this compendium describes the major production routes of the six most relevant iodine radio isotopes and the various methods of labeling molecules of biological, diagnostic or pharmaceutical interest with them. The chapters describe the basic reaction mechanisms, and the influence of iodine introduction on physical/chemical and pharmacological properties. They also include examples of important reaction pathways for the preparation of radio-iodine compounds. The volume is completed by an expert system providing guidelines to obtain the most suitable method of synthesis regarding also cost and time aspects. Worked examples support the novices confronted with radio-iodination reactions. 
650 0 |a Chemistry. 
650 0 |a Analytical chemistry. 
650 0 |a Organic chemistry. 
650 0 |a Physical chemistry. 
650 0 |a Medicinal chemistry. 
650 1 4 |a Chemistry. 
650 2 4 |a Organic Chemistry. 
650 2 4 |a Analytical Chemistry. 
650 2 4 |a Physical Chemistry. 
650 2 4 |a Medicinal Chemistry. 
700 1 |a COENEN, HEINZ H.  |e editor. 
700 1 |a MERTENS, JOHN.  |e editor. 
700 1 |a MAZIEÈRE, BERNARD.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
776 0 8 |i Printed edition:  |z 9781402045608 
856 4 0 |u http://dx.doi.org/10.1007/1-4020-4561-1  |z Full Text via HEAL-Link 
912 |a ZDB-2-CMS 
950 |a Chemistry and Materials Science (Springer-11644)