Smad Signal Transduction Smads in Proliferation, Differentiation and Disease /

For the first time world-leading experts in the area of cellular signaling have joined to the production of a book on Smad signal transduction. Smads are the principal intracellular effectors of TGF-b family members that control numerous cellular responses with critical roles in development and in t...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Dijke, Peter ten (Επιμελητής έκδοσης), Heldin, Carl-Henrik (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Dordrecht : Springer Netherlands, 2006.
Σειρά:Proteins and Cell Regulation ; 5
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Molecular Evolution of Smad Proteins
  • C. Elegans TGF-? Signaling Pathways
  • Smads In Drosophila – Interpretation Of Graded Signals In Vivo
  • Delineating the TGF-?/Smad-Induced Cytostatic Response
  • Smads In Mesenchymal Differentiation
  • Smad Proteins in Apoptotic and Survival Signaling
  • TGF-?/SMAD Signaling in Epithelial to Mesenchymal Transition
  • Genetic Disruptions within the Murine Genome Reveal Numerous Roles of the Smad Gene Family in Development, Disease, and Cancer
  • Trafficking of Serine/Threonine Kinase Receptors and Smad Activation
  • Nucleocytoplasmic Shuttling of Smad Proteins
  • Structural Insights into Smad Function and Specificity
  • Regulation of Smad Function by Phosphorylation
  • Regulation of Smad Functions Through Ubiquitination and Sumoylation Pathways
  • Smad Transcriptional Co-Activators and Co-Repressors
  • Integration of Signaling Pathways Via Smad Proteins
  • Interplays Between The Smad and Map Kinase Signaling Pathways
  • Gene Expression Signatures of TGF-?/Smad-Induced Responses
  • Systems Biology Approaches to TGF-?/Smad Signaling
  • Inhibitory Smads: Mechanisms of Action and Roles in Human Diseases
  • Alterations in Smad Signaling in Carcinogenesis
  • TGF-? Receptor Kinase Inhibitors for the Treatment of Cancer
  • TGF-? Receptor Kinase Inhibitors for Treatment of Fibrosis.