Cell Adhesion and Cytoskeletal Molecules in Metastasis

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Cress, Anne E. (Επιμελητής έκδοσης), Nagle, Raymond B. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Dordrecht : Springer Netherlands, 2006.
• Σειρά: Cancer Metastasis – Biology and Treatment, 9
• Θέματα: Medicine.; Cancer research.; Molecular biology.; Dermatology.; Oncology.; Pathology.; Surgery.; Medicine & Public Health.; Cancer Research.; Molecular Medicine.
• Φυσική περιγραφή: XII, 196 p. online resource.
• ISBN: 9781402051296
• ISSN: 1568-2102 ;

In this volume, the expression of specific adhesion molecules within human cancer tissues are highlighted. The expression signatures from published DNA microarray and immunohistochemistry studies are detailed. The concept that the alteration of specific adhesion molecules influence the cancer migration ability and cancer damage responses is detailed in this volume; both features are essential for the survival of an invading tumor cell. Defining the minimal adhesion receptors preserved on cancer cells during tumor progression will define the metastatic adhesion signature. Understanding the metastatic adhesion signature will reveal vulnerabilities that could be exploited for the prevention and/or eradication of the invading cancer cell.