Yeast as a Tool in Cancer Research

Leland H. Hartwell Director, Fred Hutchinson Cancer Research Center, Nobel Laureate for Medicine, 2001 Yeast has proved to be the most useful single-celled organism for studying the fundamental aspects of cell biology. Resources are now available for yeast that greatly simplify and empower new inves...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Nitiss, John L. (Editor), Heitman, Joseph (Editor)
Format: Electronic eBook
Language:English
Published: Dordrecht : Springer Netherlands, 2007.
Subjects:
Online Access:Full Text via HEAL-Link
Table of Contents:
  • From DNA Replication to Genome Instability in Schizosaccharomyces Pombe: Pathways to Cancer
  • Dissecting Layers of Mitotic Regulation Essential for Maintaining Genomic Stability
  • Yeast as a Tool in Cancer Research: Nuclear Trafficking
  • Studies of Protein Farnesylation in Yeast
  • From Bread to Bedside: What Budding Yeast has Taught us about the Immortalization of Cancer Cells
  • HSP90 Co-Chaperones in Saccharomyces Cerevisiae
  • Yeast as a Model System for Studying Cell Cycle Checkpoints
  • Metabolism and Function of Sphingolipids in Saccharomyces Cerevisiae: Relevance to Cancer Research
  • Exploring and Restoring the p53 Pathway Using the p53 Dissociator Assay in Yeast
  • Functional Analysis of the Human p53 Tumor Suppressor and its Mutants Using Yeast
  • ABC Transporters in Yeast – Drug Resistance and Stress Response in a Nutshell
  • The FHCRC/NCI Yeast Anticancer Drug Screen
  • Yeast as a Model to Study the Immunosuppressive and Chemotherapeutic Drug Rapamycin
  • Use of Yeast as a Model System for Identifying and Studying Anticancer Drugs
  • Genetic Analysis of Cisplatin Resistance in Yeast and Mammals
  • Using Yeast Tools to Dissect the Action of Anticancer Drugs: Mechanisms of Enzyme Inhibition and Cell Killing by Agents Targeting DNA Topoisomerases.