Molecular Mechanisms of Cancer

• Main Author: Weber, Georg F. (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Dordrecht : Springer Netherlands, 2007.
• Subjects: Medicine.; Cancer research.; Molecular biology.; Oncology.; Cell biology.; Biomedicine.; Cancer Research.; Molecular Medicine.; Cell Biology.

Cancer may constitute the most extensively studied functions constitute a second line of defense that disease entity of our time. Nevertheless, our com- protects against transforming defects in oncogenes prehension of the cellular and molecular pathology or tumor-suppressor genes and are here consid...

Table of Contents:

• General Mechanisms of Transformation
• Theories of Carcinogenesis
• Physiologic Correlates of Malignancy
• Alterations Intrinsic to the Tumor Cells
• Cell Division and Survival
• Cellular Senescence
• Invasiveness
• Mechanisms of Regulation of Cancer-related Genes
• DNA Repair
• Epigenetic Regulation of Cancer-Associated Gene Products
• Interaction of the Groups of Cancer-Related Gene Products
• Interactions Between Host and Tumor
• Structural Growth Control
• The Organ Preference of Metastasis Formation
• Angiogenesis
• Interactions with the Immune System
• Endocrine Dysregulation
• Dormancy and Minimal Residual Disease
• Molecular Mechanisms of Individual Malignancies
• Epithelial Tumors
• Hematologic Malignancies
• Mesenchymal Tumors
• Neurologic Tumors
• Tumors of Serous Cavities
• Embryonic Tumors.