The Aetiology of Deep Venous Thrombosis A Critical, Historical and Epistemological Survey /

• Κύριοι συγγραφείς: Malone, P. Colm (Συγγραφέας), Agutter, Paul S. (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Dordrecht : Springer Netherlands, 2008.
• Θέματα: Medicine.; Medicine > Philosophy.; Hematology.; Pathology.; Vascular surgery.; Medicine > History.; Medicine & Public Health.; History of Medicine.; Vascular Surgery.; Philosophy of Medicine.

What we now call ‘deep venous thrombosis’ (DVT) has been studied in diverse ways during the last 200–300 years. Each of these approaches contributes to a full modern understanding of aetiology. Therefore, much of this book is a historical survey of the field. However, our remit is broader than the t...

Πίνακας περιεχομένων:

• to the Study of Deep Venous Thrombosis
• The Coagulation Cascade and the Consensus Model of DVT
• Hypercoagulability
• Historical Roots
• Coagulation and its Disorders: A History of Haematological Research
• Virchow and the Pathophysiological Tradition in the 19th Century
• The Pathophysiological Tradition after Virchow
• Interrupted Circulation: The ‘Stasis’ Hypothesis and the Significance of Venous Valves
• Underperfusion of Valve Pockets and the Initiation of DVT
• The Role of Endothelial Hypoxia in DVT
• The Valve Cusp Hypoxia Hypothesis
• Molecular Changes in the Hypoxic Endothelium
• Cadaver Clots or Agonal Thrombi?.