Therapeutic Resistance to Anti-Hormonal Drugs in Breast Cancer New Molecular Aspects and their Potential as Targets /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Hiscox, Stephen (Επιμελητής έκδοσης), Gee, Julia (Επιμελητής έκδοσης), Nicholson, Robert I. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Dordrecht : Springer Netherlands, 2009.
• Θέματα: Medicine.; Cancer research.; Oncology.; Biomedicine.; Cancer Research.

One of the main causes of failure in the treatment of breast cancer is the intrinsic presence of, or development of, drug resistance by the cancer cells. Recent studies on the mechanisms of cancer drug resistance have yielded important information highlighting both how tumour cells may escape these...

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• Experimental Endocrine Resistance: Concepts and Strategies
• Transcriptional Coactivators and Corepressors in Endocrine Response and Resistance in Breast Cancer
• The Re-Expression of Estrogen Receptor in Estrogen Receptor-Negative Breast Cancer and Restoration of Anti-Estrogen Responses
• The Dark Side of Antihormonal Action in Breast Cancer
• Influence of the Tumour Microenvironment
• Are Stem-Like Cells Responsible for Resistance to Therapy in Breast Cancer?
• HSP90 Inhibition as an Anticancer Strategy: Novel Approaches and Future Directions
• Adverse Features of Acquired Antihormone Resistance and Their Targeting
• Identifying Modifiers of Tamoxifen Sensitivity Using High-Throughput Genetic and Chemical Screens
• Endocrine Resistance in Breast Cancer- Where Are We NowWith Intelligent Combination Therapies?.