Epigenomics

• Corporate Author: SpringerLink (Online service)
• Other Authors: Ferguson-Smith, Anne C. (Editor), Greally, John M. (Editor), Martienssen, Robert A. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Dordrecht : Springer Netherlands, 2009.
• Subjects: Medicine.; Biomedicine.; Biomedicine general.

Epigenetic modifications act on DNA and its packaging proteins, the histones, to regulate genome function. Manifest as the heritable methylation of DNA and as post-translational histone modifications, these molecular flags influence the architecture and integrity of the chromosome, the accessibility...