Cancer Microenvironment and Therapeutic Implications Tumor Pathophysiology Mechanisms and Therapeutic Strategies /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Baronzio, Gianfranco (Επιμελητής έκδοσης), Fiorentini, Gianfranco (Επιμελητής έκδοσης), Cogle, Christopher R. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Dordrecht : Springer Netherlands, 2009.
• Έκδοση: 1.
• Θέματα: Medicine.; Cancer research.; Oncology.; Pathology.; Biomedicine.; Cancer Research.

In the post-genomic era, cancer is a genetic disease. However, cancer genotype does not always equal cancer phenotype. Cancers with the same genetic abnormalities don’t always behave the same. Understanding and eradicating cancers will require an appreciation for cancer’s ecology. This book is the f...

Πίνακας περιεχομένων:

• Tumor Physiopathology and Microenvironment Genesis
• Inflammation and Carcinogenesis: A Change in the Metabolic Process
• Tumor Microenvironment: Aspects of Stromal-Parenchymal Interaction
• Significance of Tumor Microenvironment on the Genesis of: Interstitial Fluid, Angiogenesis, Haemostatic/Haemorheologic Abnormalities. Pathogenesis and Therapeutic Aspects
• Cancer, Stem Cells and the Neoplastic Niche
• Tumor Microenvironment, Therapeutic Perspectives and Strategies for Normalization
• Barriers to Drug Delivery in Cancer: Clinical Implications
• Hypoxia, Hyperthermia, Chemotherapy: Interactions and Opportunities
• Effects of Molecularly Targeting Hypoxia in Oncology
• Significance of the Tumour Microenvironment in Radiotherapy
• Effects of Tumor Microenvironment on Immunity and Consequent Clinical Considerations
• Effects of Tumor Microenvironment on Hyperthermia, Photodynamic and Nanotherapy
• Targeting Tumour Vascularization from Bench to Bedside: Suggestions for Combination with Hyperthermia
• New Indications for Established Drugs Able to Modify Tumour-Host Interactions.