Oral Delivery of Macromolecular Drugs Barriers, Strategies and Future Trends /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Bernkop-Schnürch, Andreas (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer US, 2009.
• Θέματα: Medicine.; Pharmacology.; Biochemistry.; Cell biology.; Biomedicine.; Pharmacology/Toxicology.; Biochemistry, general.; Cell Biology.

Due to a rapid development in biotechnology more and more macromolecular drugs such as therapeutic peptides, oligosaccharides and nucleic acids are entering the pharmaceutical arena representing unprecedented challenges from the drug delivery point of view. One of the likely greatest challenges is t...

Πίνακας περιεχομένων:

• Enzymatic Barriers
• Gastrointestinal Mucus Gel Barrier
• The Absorption Barrier
• Strategies to Overcome the Enzymatic Barrier
• Low Molecular Mass Permeation Enhancers in Oral Delivery of Macromolecular Drugs
• Polymeric Permeation Enhancers
• Strategies to Overcome Efflux Pumps
• Multifunctional Polymeric Excipients in Oral Macromolecular Drug Delivery
• Nano- and Microparticles in Oral Delivery of Macromolecular Drugs
• Liposome-Based Mucoadhesive Formulations for Oral Delivery of Macromolecules
• Strategies in Oral Immunization
• Oral Delivery of Nucleic Acid Drugs.