V(D)J Recombination

v(D)J recombination: for the community of immunologists and developmental biologists, the molecular route by which B and T lymphocytes acquire their unique function of affording adaptive immunity. Yet, for many-from experienced scientists to trainees-it represents a (rather too) sophisticated proces...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Ferrier, Pierre (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: New York, NY : Springer New York, 2009.
Σειρά:Advances in Experimental Medicine and Biology, 650
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Early Steps of V(D)J Rearrangement: Insights from Biochemical Studies of RAG-RSS Complexes
  • Regulation of RAG Transposition
  • Recent Insights into the Formation of RAG-Induced Chromosomal Translocations
  • V(D)J Recombination Deficiencies
  • Large-Scale Chromatin Remodeling at the Immunoglobulin Heavy Chain Locus: A Paradigm for Multigene Regulation
  • Genetic and Epigenetic Control of V Gene Rearrangement Frequency
  • Dynamic Aspects of TCR? Gene Recombination: Qualitative and Quantitative Assessments of the TCR? Chain Repertoire in Man and Mouse
  • Germline Transcription: A Key Regulator of Accessibility and Recombination
  • Dynamic Regulation of Antigen Receptor Gene Assembly
  • Molecular Genetics at the T-Cell Receptor ? Locus: Insights into the Regulation of V(D)J Recombination
  • Molecular Pathways and Mechanisms Regulating the Recombination of Immunoglobulin Genes during B-Lymphocyte Development
  • Regulation of V(D)J Recombination by E-Protein Transcription Factors
  • Temporal and Spatial Regulation of V(D)J Recombination: Interactions of Extrinsic Factors with the RAG Complex
  • V(D)J Recombination: Of Mice and Sharks
  • Normal and Pathological V(D)J Recombination: Contribution to the Understanding of Human Lymphoid Malignancies.