Development and Engineering of Dopamine Neurons

• Corporate Author: SpringerLink (Online service)
• Other Authors: Pasterkamp, R. Jeroen (Editor), Smidt, Marten P. (Editor), Burbach, J. Peter H. (Editor)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York, 2009.
• Series: Advances in Experimental Medicine and Biology, 651
• Subjects: Medicine.; Biomedicine.; Biomedicine general.

Theneurotransmitter dopamine has just celebrated its 50thbirthday. The discovery of dopamine as a neuronal entity in the late 1950s and the notion that it serves in neurotransmission has been a milestone in the field of neuroscience research. This milestone marked the beginning of an era that explor...

Table of Contents:

• Development of the Dopamine Systems in Zebrafish
• Dopamine Systems in the Forebrain
• The Role of Otx Genes in Progenitor Domains of Ventral Midbrain
• Terminal Differentiation of Mesodiencephalic Dopaminergic Neurons:
• Foxa1 and Foxa2 Transcription Factors Regulate Differentiation of Midbrain Dopaminergic Neurons
• Transcriptional Regulation of Their Survival:
• Neurotrophic Support of Midbrain Dopaminergic Neurons
• TGF-? in Dopamine Neuron Development, Maintenance and Neuroprotection
• Axon Guidance in the Dopamine System
• Protocols for Generating ES Cell-Derived Dopamine Neurons
• Molecular and Cellular Determinants for Generating ES-Cell Derived Dopamine Neurons for Cell Therapy.