The Role of Genetics in Breast and Reproductive Cancers

Of all factors contributing to breast cancer, family history of disease is the most powerful. Currently, our understanding of genetic predisposition to breast cancer includes three classes of genes as defined by their associated risks. BRCA1 and BRCA2 are high-penetrance breast cancer predisposition...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Welcsh, Piri (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: New York, NY : Springer New York, 2010.
Σειρά:Cancer Genetics
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Recognition of Hereditary Breast and Reproductive Cancer Syndromes
  • Cancer Genetics in the Clinic: The Challenges and Responsibilities of Counseling and Treating Women at Risk
  • Management of Women with Inherited BRCA1 and BRCA2 Mutations
  • Genetic etiology of breast and reproductive cancers
  • Unclassified Variants in the Breast Cancer Susceptibility Genes BRCA1 and BRCA2
  • Recent Advances in Understanding the Cellular Functions of BRCA1
  • Recent Advances in Understanding the Cellular Functions of BRCA2
  • Genetic Modifiers of Risk of BRCA1- and BRCA2-Related Breast and Ovarian Cancers
  • Other Hereditary Breast Cancer Syndromes and Genes
  • Ovarian and Endometrial Cancer in Patients with Hereditary Non-polyposis Colorectal Cancer Syndrome
  • Somatic Alterations and Implications in Breast Cancer
  • Somatic Genetic Development in Epithelial Ovarian Cancer
  • Genes and the environment
  • High-Frequency Low-Penetrance Alleles
  • Host and Viral Genetics and Risk of Cervical Cancer
  • Estrogen-Metabolizing Gene Polymorphisms, Genetic Susceptibility, and Pharmacogenomics
  • The Future of Discoveries in Breast and Reproductive Cancers: The Genome and Epigenetics.