| Περίληψη: | Personalized medicine is the concept that selection of a treatment should be tailored according to the individual patient’s specific characteristics, including age, gender, height/weight, ethnicity, diet, and environment , versus a decision based on ‘standards of care’ derived by averaging responses across large cohorts of individuals in clinical trials. This alternate approach has only been possible as a result of the translation and integration of several new technologies in clinical care. As the first definitive work on this topic, Textbook of Personalized Medicine reviews the fundamentals and development of personalized medicine, and subsequent adoptions of the concepts by the biopharmaceutical industry and the medical profession. It also discusses examples of applications in key therapeutic areas, as well as ethical and regulatory issues. The textbook will serve as a convenient source of information for physicians, scientists, decision makers in the biopharmaceutical and healthcare industries, and interested members of the public. Contents: Basics of Personalized Medicine Molecular Diagnostics as Basis of Personalized Medicine Role of Biomarkers in Personalized Medicine Pharmacogenetics Pharmacogenomics Pharmacoproteomics Metabolomics Personalized Biological Therapies Development of Personalized Therapy Personalized Therapy of Cancer Personalized Management of Cardiovascular Disorders Personalized Management of Miscellaneous Disorders Personalized preventive medicine Organization of Personalized Medicine Ethical and Regulatory Aspects of Personalized Medicine Economics of Personalized Medicine Future of Personalized Medicine About the Author Professor K. K. Jain is trained in neurosurgery with specialist qualifications. He worked for 25 years in various academic positions and private practice worldwide mostly in Canada and the US. His clinical research interests during these years were use of lasers for microneurosurgery and hyperbaric oxygen. He has been involved in biotechnology since 1989, when he moved to Basel, Switzerland. He was elected a fellow of the Faculty of Pharmaceutical Medicine of the Royal Colleges of UK in 2000. He is the author of over 405 publications including 15 books and 48 special reports. Important books are Textbook of Gene Therapy, Textbook of Hyperbaric Medicine and Handbook of Nanomedicine. He is a member of editorial board of several journals and senior associate editor of MedLink Neurology (San Diego, California), a continuing education program for neurologists. Prof. Jain has been interested in integrating various biotechnologies to develop personalized medicine since 1997. He wrote the first report on personalized medicine, which was published in 1998 by Decision Resources Inc. The report titled Personalized Medicine: scientific and commercial aspects is continuously updated and published at Jain PharmaBiotech, Basel. He lectures and conducts workshops worldwide.
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