Cell-Extracellular Matrix Interactions in Cancer

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Zent, Roy (Επιμελητής έκδοσης), Pozzi, Ambra (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York, 2010.
• Έκδοση: 1.
• Θέματα: Medicine.; Cancer research.; Pharmacology.; Cell biology.; Biomedicine.; Cancer Research.; Cell Biology.; Pharmacology/Toxicology.

Cells require interactions with extracellular matrix (ECM) components in order to undergo normal morphogenesis with respect to organogenesis. ECM plays a significant role in regulating numerous cellular functions, like cell shape, adhesion, migration, proliferation, polarity, differentiation and apo...

Πίνακας περιεχομένων:

• The Extracellular Matrix: An Overview
• Integrin Structure and Function
• Cancer in Context: Importance of the Tumor Microenvironment
• Basement Membrane Collagens and Cancer
• Laminins and Cancer Progression
• Fibronectins and Their Receptors in Cancer
• Vitronectin-Binding Integrins in Cancer
• The Function of SPARC in Tumor Cell Biology: SPARC as a Modulator of Cell–Extracellular Matrix Interaction
• Proteoglycans and Cancer
• Tetraspanins in Cancer
• The Role of Integrin-Linked Kinase in Cancer Development and Progression
• Focal Adhesion Kinase with the Interacting Proteins and Signaling in Cancer.