Molecular Basis for Therapy of AIDS-Defining Cancers

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Dittmer, Dirk P. (Επιμελητής έκδοσης), Krown, Susan E. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2010.
• Θέματα: Medicine.; Cancer research.; Pharmacology.; Infectious diseases.; Biomedicine.; Cancer Research.; Pharmacology/Toxicology.; Infectious Diseases.

An increased risk for various cancers is a characteristic of people living with HIV infection. Although only three cancers – Kaposi’s sarcoma, high-grade B-cell lymphomas, and invasive cervical cancer – are considered to be "AIDS-defining" conditions, are associated with oncogenic viruses,...

Πίνακας περιεχομένων:

• The Epidemiology of Cancer in People with HIV
• Epidemiology and Clinical Characteristics of Non-AIDS-Defining Malignancies
• HIV-Related Cancer Management in Resource-Limited Settings: A Case Study of Malawi
• Immunology of HIV-Associated Kaposi Sarcoma
• Targeting Signal Transduction Pathways for the Treatment of Kaposi Sarcoma
• Role of NF-?B Inhibitors in HIV-Related Malignancies
• The Molecular Basis of Lytic Induction Therapy in Relation to Gamma herpesvirus (KSHV, EBV)-Associated, AIDS-Related Tumors
• Viral Interleukin-6: Molecular Biology and Pathogenesis
• Targeting the PI3K/Akt/mTOR Pathway in AIDS-Associated Malignancies
• Restoration of p53 Function by MDM2 Inhibition: Potential Strategy to Treat KSHV-Associated Malignancies
• Interferon in Kaposi’s Sarcoma Biology and Therapy
• Metronomic Therapy for HIV-Associated Malignancies
• Targeting EGFR in HPV-Associated Cancer
• Cidofovir Against Human Papillomavirus-Associated Diseases.