SuperMEN1 Pituitary, Parathyroid and Pancreas /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Balogh, Katalin (Επιμελητής έκδοσης), Patocs, Attila (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York, 2010.
• Σειρά: Advances in Experimental Medicine and Biology, 668
• Θέματα: Medicine.; Biomedicine.; Biomedicine general.

The vast expansion in research on tumorigenesis has greatly increased our understanding of tumor development in patients with inherited endocrine tumor syndromes. This book provides an up-to-date summaryfrom clinical basics and latest follow-up guidelines to the most recent molecular findings in mul...

Πίνακας περιεχομένων:

• MEN1 Clinical Background
• Genetic Background of MEN1: From Genetic Homogeneity to Functional Diversity
• Menin: The Protein Behind the MEN1 Syndrome
• Cellular Functions of Menin
• The Role of Menin in Hematopoiesis
• Role of Menin in Bone Development
• Activin, TGF-? and Menin in Pituitary Tumorigenesis
• The Role of Menin in Parathyroid Tumorigenesis
• Role of Menin in Neuroendocrine Tumorigenesis
• Adrenal Tumors in MEN1 Syndrome and the Role of Menin in Adrenal Tumorigenesis
• Functional Studies of Menin through Genetic Manipulation of the Men1 Homolog in Mice.