Proteins Membrane Binding and Pore Formation

• Corporate Author: SpringerLink (Online service)
• Other Authors: Anderluh, Gregor (Editor), Lakey, Jeremy (Editor)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York, 2010.
• Series: Advances in Experimental Medicine and Biology, 677
• Subjects: Medicine.; Molecular biology.; Biomedicine.; Biomedicine general.; Molecular Medicine.

Formation of transmembrane pores is a very effective way of killing cells. It is thus not surprising that many bacterial and eukaryotic toxic agents are pore-forming proteins. Pore formation in a target membrane is a complex process composed of several steps; proteins need to attach to the lipid mem...