Conjugation and Deconjugation of Ubiquitin Family Modifiers Subcellular Biochemistry /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Groettrup, Marcus (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York, 2010.
• Σειρά: Subcellular Biochemistry, 54
• Θέματα: Life sciences.; Human physiology.; Molecular biology.; Proteins.; Life Sciences.; Protein Science.; Human Physiology.; Molecular Medicine.

† 1 a a 4 † 17 10 15 ubiquitin; and of 16 VCP 17 18 20 33 34 34 36 p domain. 41 42 42 43 P U 42 47 binding. C. elegans 16 In 21 22 50 51 52 53 13 and UFD 4 10 of Cdc48. 18 30 of Ufd2. COFACTORS 47 23 13 47 47 47 72 15 15 and of Spt23 p90. Ufd2 and Cdc48. In C. elegans 74 16 75 75 76 76 Ufd2 25 54 54...

Πίνακας περιεχομένων:

• Activation of Ubiquitin and Ubiquitin-Like Proteins
• Control of Ubiquitin Conjugation by Cdc48 and Its Cofactors
• Regulation of Ubiquitin Receptors by Coupled Monoubiquitination
• Control of Cullin-Ring Ubiquitin Ligase Activity by Nedd8
• Control of Deneddylation by the COP9 Signalosome
• Mechanism, Specificity and Structure of the Deubiquitinases
• Ubiquitin Conjugation and Deconjugation in NF-?B Signaling
• Functions of Linear Ubiquitin Chains in the NF-?B Pathway
• Assembly of K11-Linked Ubiquitin Chains by the Anaphase-Promoting Complex
• Ubiquitin Family Members in the Regulation of the Tumor Suppressor p53
• Ubiquitylation in the ERAD Pathway
• Pupylation
• Sumo Control
• The In Vivo Functions of Desumoylating Enzymes
• Regulatory Functions of Ubiquitin and SUMO in DNA Repair Pathways
• Sumoylation as a Signal for Polyubiquitylation and Proteasomal Degradation
• In Vivo Functions of Isgylation
• Identification and Validation of ISG15 Target Proteins
• FAT10.