Biophysical Regulation of Vascular Differentiation and Assembly

The ability to grow stem cells in the laboratory and to guide their maturation to functional cells allows us to study the underlying mechanisms that govern vasculature differentiation and assembly in health and disease. Accumulating evidence suggests that early stages of vascular growth are exquisit...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Gerecht, Sharon (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: New York, NY : Springer New York, 2011.
Έκδοση:1.
Σειρά:Biological and Medical Physics, Biomedical Engineering,
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
LEADER 03807nam a22005175i 4500
001 978-1-4419-7835-6
003 DE-He213
005 20151030061410.0
007 cr nn 008mamaa
008 110105s2011 xxu| s |||| 0|eng d
020 |a 9781441978356  |9 978-1-4419-7835-6 
024 7 |a 10.1007/978-1-4419-7835-6  |2 doi 
040 |d GrThAP 
050 4 |a QH505 
072 7 |a PHVN  |2 bicssc 
072 7 |a PHVD  |2 bicssc 
072 7 |a SCI009000  |2 bisacsh 
082 0 4 |a 571.4  |2 23 
245 1 0 |a Biophysical Regulation of Vascular Differentiation and Assembly  |h [electronic resource] /  |c edited by Sharon Gerecht. 
250 |a 1. 
264 1 |a New York, NY :  |b Springer New York,  |c 2011. 
300 |a XIV, 254 p.  |b online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |b PDF  |2 rda 
490 1 |a Biological and Medical Physics, Biomedical Engineering,  |x 1618-7210 
505 0 |a Preface -- Embryonic and Adult Stem Cells in Vasculogenesis and Angiogenesis -- Extracellular Matrix and Matrix Metalloproteinase in Vascular Morphogenesis -- Scaffolding for Three-Dimensional Embryonic Vasculogenesis -- Matrix Viscoelasticity and Remodeling During 3D Vascular Assembly -- Biomechanical Properties of Implanted Scaffolds Affect Human Blood Vessel Formation From Circulating Endothelial Colony Forming Cells -- Oxygen Regulation of Adult Angiogenesis -- Hypoxia During Embryonic Vascular Development and Differentiation -- Three-Dimensional Regulation During Cancerous Angiogenesis -- Microfluidics to Control Shear and Oxygen Flow for Vascular Differentiation -- Cyclic Strain and Surface Shape for Engineered Vasculature Constructs -- Matrix Topography and Viscoelasticity Guide Vascular Assembly. 
520 |a The ability to grow stem cells in the laboratory and to guide their maturation to functional cells allows us to study the underlying mechanisms that govern vasculature differentiation and assembly in health and disease. Accumulating evidence suggests that early stages of vascular growth are exquisitely tuned by biophysical cues from the microenvironment, yet the scientific understanding of such cellular environments is still in its infancy. Comprehending these processes sufficiently to manipulate them would pave the way to controlling blood vessel growth in therapeutic applications. This book assembles the works and views of experts from various disciplines to provide a unique perspective on how different aspects of its microenvironment regulate the differentiation and assembly of the vasculature. In particular, it describes recent efforts to exploit modern engineering techniques to study and manipulate various biophysical cues. Biophysical Regulation of Vascular Differentiation and Assembly provides an interdisciplinary view of vasculature regulation by various biophysical cues and presents recent advances in measuring and controlling such parameters. This book will be of interest to biologists, biophysicists and engineers who work with vascular differentiation and assembly. 
650 0 |a Physics. 
650 0 |a Stem cells. 
650 0 |a Biophysics. 
650 0 |a Biological physics. 
650 0 |a Biomedical engineering. 
650 1 4 |a Physics. 
650 2 4 |a Biophysics and Biological Physics. 
650 2 4 |a Biomedical Engineering. 
650 2 4 |a Stem Cells. 
700 1 |a Gerecht, Sharon.  |e editor. 
710 2 |a SpringerLink (Online service) 
773 0 |t Springer eBooks 
776 0 8 |i Printed edition:  |z 9781441978349 
830 0 |a Biological and Medical Physics, Biomedical Engineering,  |x 1618-7210 
856 4 0 |u http://dx.doi.org/10.1007/978-1-4419-7835-6  |z Full Text via HEAL-Link 
912 |a ZDB-2-PHA 
950 |a Physics and Astronomy (Springer-11651)