Characterization of Protein Therapeutics using Mass Spectrometry

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Chen, Guodong (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Boston, MA : Springer US : Imprint: Springer, 2013.
• Θέματα: Chemistry.; Human genetics.; Pharmaceutical technology.; Mass spectrometry.; Biotechnology.; Proteins.; Materials science.; Mass Spectrometry.; Protein Science.; Pharmaceutical Sciences/Technology.; Human Genetics.; Characterization and Evaluation of Materials.

Protein therapeutics’ high efficacy, safety, and ability to treat life-threatening diseases such as cancer, inflammation and genetic disorders have revolutionized modern medicine. In 2012, 200 companies competed in this $90 billion year industry.   In Characterization of Protein Therapeutics using M...

Πίνακας περιεχομένων:

• Characterization of Protein Therapeutics by Mass Spectrometry: Recent Developments and Future Directions
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• Disulfide Linkages of an Albumin Fusion Protein
• Detailed Structural Characterization of Monoclonal Antibodies
• Application of Protein Mass Spectrometry in Impurity and Degradant Characterization
• Mass Spectrometry Methods to Analyze Higher Order Structure of Protein Therapeutics by Chemical Footprinting
• Aglycosylations Alters Protein Conformation in Antibodies Engineered with Specific Effector Functions Using HDX-MS
• Characterizing Biotherapeutic Protein 3D Structures by Electrospray Ion-Mobility Mass Spectrometry
• Oxford University, Characterization of Assemblies of Proteins by Mass Spectrometry.  .