Understanding the Dynamics of Biological Systems Lessons Learned from Integrative Systems Biology /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Dubitzky, Werner (Editor), Southgate, Jennifer (Editor), Fuß, Hendrik (Editor)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York : Imprint: Springer, 2011.
• Subjects: Life sciences.; Bioinformatics.; Systems biology.; Computational biology.; Life Sciences.; Systems Biology.; Computer Appl. in Life Sciences.

Systems biology has risen as a direct result of the limitation of conventional (reductionistic) biology to understand complex phenomena emerging as a result of dynamic and multiscale biological interactions. By applying mathematical and computational models, systems biologists integrate the elementa...

Table of Contents:

• Preface
• Effects of Protein Quality Control Machinery on Protein Homeostasis
• Metabolic Network Dynamics: Properties and Principles
• A Deterministic, Mathematical Model for Hormonal Control of the Menstrual Cycle
• Modelling Transport Processes and their Implications for Chemical Disposition and Action
• Systems Biology of Tuberculosis: Insights for Drug Discovery
• Qualitative Analysis of Genetic Regulatory Networks in Bacteria
• Modelling Antibiotic Resistance in Bacterial Colonies Using Agent-Based Approach
• Modelling the Spatial Pattern Forming Modules in Mitotic Spindle Assembly
• Cell-Centred Modelling of Tissue Behaviour
• Interaction-Based Simulations for Integrative Spatial Systems Biology
• Glossary
• Index.