Molecular Determinants of Radiation Response
The DNA of mammalian cells is constantly under assault from both endogenous and exogenous sources. Ionizing radiation is one of the most important sources of genomic injury because of its ability to inflict substantial cellular damage that is both therapeutic as well as mutagenic. Mammalian cells...
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| Other Authors: | , |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
New York, NY :
Springer New York,
2011.
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| Edition: | 1. |
| Series: | Current Cancer Research
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| Subjects: | |
| Online Access: | Full Text via HEAL-Link |
Table of Contents:
- Molecular Basis of the DNA Damage Responses
- ATM signaling and DNA Damage
- H2AX in DNA Damage Response
- Dynamic Imaging of DNA Damage Foci
- DNA Damage Signaling Downstream of ATM
- Checkpoint Control and Radiation
- Chromatin Responses to DNA Damage.-DNA Damage Response and Senescence
- C. elegans and DNA Damage
- Modulation of Radiation Responses – Opportunities for Therapeutic Exploitation
- The Stem Cell and Radiation
- Role of the Cell Membrane in Signaling Radiation Injury
- Hypoxia and Modulation of Cellular Radiation Response
- Role of PARP and PARP Inhibition in Cellular Response to Radiation
- Anti-angiogenic Therapies and Radiation Responses
- Gene Therapy and Radiation
- Radiation-mediated Molecular Targeting
- EGFR Signaling and Radiation
- Heat and Heat Shock Proteins Modulation of Radiation Response
- Radiation-induced Immune Modulation.
