TH17 Cells in Health and Disease

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Jiang, Shuiping (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York, 2011.
• Θέματα: Medicine.; Immunology.; Pharmaceutical technology.; Infectious diseases.; Cell biology.; Biomedicine.; Infectious Diseases.; Cell Biology.; Medicine/Public Health, general.; Pharmaceutical Sciences/Technology.

“About 25 years ago, Mosmann & Coffman introduced the TH1 / TH2 paradigm of T helper cell differentiation which helped explain many aspects of adaptive immunity from eliminating intracellular versus extracellular pathogens to induction of different types of tissue inflammation.   However, TH1 /...

Πίνακας περιεχομένων:

• From Th1/Th2 Pardigm to Th17 cells: Le Roi est Mort, Vive le Roi
• Th17 Cytokines: Characteristics, Regulation, Biological Function
• TGF-beta and Th17 cells
• A Pleiotropic Cytokine and Th17 cells
• Apoptosis and Th17 cell Differentiation
• IL-1 and Innate Immunity in the Differentiation of Th17 cells. Negative Regulation of Th17 Differentiation
• Signal Transduction in Th17 cell Differentiation
• Structure and IL-17 Receptor Signaling
• Trafficking Receptors and Migration of Th17 cell Subsets
• Plastic T cells: Recycling Effector Functions
• Human Th17 cells
• Th17 Cytokines in Primary Mucosal Immunity
• Th17 cells and IL-23 in Gut Inflammation
• The Roles of IL17A and IL17F in Mucosal Infection and Allergy
• Th17 cells in Fungal Infections
• IL-17 cells in Organ Transplantation Rejection and Tolerance
• Th17 cells, Proteins Associated with Th17 Polarization, and their Role in Graft versus Host Disease
• Interplay of Pathogenic Th1/Th17 cells and Regulatory T cells in Auto-immune Disease: A tale of Yin and Yang
• The Role of Interleukin-17 in Systemic Lupus Erythematosus
• IL-17 in B cell Biology and Systemic Lupus Erythematosus
• IL-17 and Th17 cells in Human Rheumatoid Arthritis
• The Role of IL-23/Th17 Immune Pathway in the Pathogenesis of Arthritis
• The Roles of IL-22 and its Related Family Members in the Pathogenesis of Psoriasis
• Th17 Pathway in Psoriasis and INflammatory Skin Diseases
• Th17 cells in the Tumor Micro-environment
• IL-17-producing NKT cells in Airway Inflammation
• IL-17-producing T cells in Auto-immune Disease.