Sample Preparation of Pharmaceutical Dosage Forms Challenges and Strategies for Sample Preparation and Extraction /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Nickerson, Beverly (Editor)
• Format: Electronic eBook
• Language: English
• Published: Boston, MA : Springer US, 2011.
• Subjects: Medicine.; Pharmacy.; Pharmacology.; Pharmaceutical technology.; Biochemistry.; Biomedicine.; Pharmacology/Toxicology.; Pharmaceutical Sciences/Technology.; Biochemistry, general.

Designed as a resource guide for analytical scientists working in the pharmaceutical industry, this comprehensive guide is focused entirely on sample preparation and extraction of pharmaceutical dosage forms.    This book is divided into four parts: •          Part One covers dosage form and diluent...

Table of Contents:

• Properties that Impact Sample Preparation and Extraction of Pharmaceutical Dosage Forms
• Sampling Considerations
• Agitation and Particle Size Reduction Techniques
• Liquid-Liquid and Solid-Phase Extraction Techniques
• Extraction Techniques Leveraging Elevated Temperature and Pressure
• Addressing Drug-Excipient Interactions
• Sample Preparation for Solid Oral Dosage Forms
• Sample Preparation for Select Non Solid Dosage Forms
• Post-Extraction Considerations
• Sample Preparation Method Validation
• Application of Quality by Design (QbD)  Principles for Sample Preparation
• Automation and Sample Preparation
• A Systematic Approach for Investigating Aberrant Potency Values
• Green Chemistry Considerations for Sample Preparation
• No Sample Preparation.