Drug Product Development for the Back of the Eye
This comprehensive volume discusses approaches for a systematic selection of delivery systems for various classes of therapeutic agents including small molecule, protein, and nucleic acid drugs. Specific topics covered in this book include: Solution, suspension, gel, nanoparticle, microparticle, and...
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| Other Authors: | , |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Boston, MA :
Springer US,
2011.
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| Series: | AAPS Advances in the Pharmaceutical Sciences Series,
2 |
| Subjects: | |
| Online Access: | Full Text via HEAL-Link |
Table of Contents:
- Selection of Drug Delivery Approaches for the Back of the Eye: Opportunities and Unmet Needs
- Microdialysis for Vitreal Pharmacokinetics
- Fluorophotometry for Pharmacokinetic Assessment
- Systemic Route for Retinal Drug Delivery: Role of the Blood-Retinal Barrier
- Topical Drug Delivery to the Back of the Eye
- Principles of Retinal Drug Delivery from Within the Vitreous
- Transscleral Drug Delivery
- Suprachoroidal and Intrascleral Drug Delivery
- Advances in Biodegradable Ocular Drug Delivery Systems
- Microparticles as Drug Delivery Systems for the Back of the Eye
- Nanotechnology and Nanoparticles
- Hydrogels for Ocular Posterior Segment Drug Delivery
- Refillable Devices for Therapy of Ophthalmic Diseases
- Targeted Drug Delivery to the Eye Enabled by Microneedles
- Ocular Iontophoresis
- Drug and Gene Therapy Mediated by Physical Methods
- Protein Drug Delivery and Formulation Development
- Drug Suspension Development for the Back of the Eye
- Regulatory Considerations in Product Development for Back of the Eye
- Clinical Endpoints for Back of the Eye Diseases
- Druggable Targets and Therapeutic Agents for Disorders of the Back of the Eye
- Development of Bile Acids as Anti-Apoptotic and Neuroprotective Agents in Treatment of Ocular Disease.
