Functional Coherence of Molecular Networks in Bioinformatics

• Corporate Author: SpringerLink (Online service)
• Other Authors: Koyutürk, Mehmet (Editor), Subramaniam, Shankar (Editor), Grama, Ananth (Editor)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York, 2012.
• Subjects: Life sciences.; Computer science.; Bioinformatics.; Systems biology.; Biomedical engineering.; Life Sciences.; Systems Biology.; Computational Biology/Bioinformatics.; Computer Science, general.; Biomedical Engineering.

A fundamental problem in life sciences is the characterization of biological function. In medical sciences, understanding the bases of functional anomalies holds the key to effective diagnosis, treatment,  and prognosis; in genetics, functional annotation of genetic variability uncovers the complex...

Table of Contents:

• Introduction to Network Biology
• Topological Characteristics of Molecular Networks
• Functional Annotation in Gene Networks
• Proteome Network Emulating Models
• Biological Network Alignment
• Pattern Mining across many Massive Biological Networks
• Molecular Networks and Complex Diseases
• Moving Towards Genome-Scale Kinetic Models: The Mass Action Stoichiometric Simulation Approach
• Index.