Epilepsy Animal and Human Correlations /

Correlation is a vital element in epilepsy research, especially given the condition’s notorious resistance to treatment. With a current ‘rate of translation’ estimated at between seven and nine years, and a translation ‘success rate’ of below 50 per cent, there is room for improvement in the correla...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριος συγγραφέας: McCandless, David W. (Συγγραφέας)
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: New York, NY : Springer New York, 2012.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
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245 1 0 |a Epilepsy  |h [electronic resource] :  |b Animal and Human Correlations /  |c by David W. McCandless. 
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505 0 |a Prologue: World Health Concerns, Incidence, Costs, etc -- Section 1 Animal Partial -- Chapter 1: Simple Partial -- Chapter 2: Complex Partial -- Section 2 Animal Generalized -- Chapter 3: Tonic Clonic -- Chapter 4: Tonic.-Chapter 5: Atonic -- Chapter 6: Myoclonic.-Chapter 7: Absence -- Section 3 Animal -- Chapter 8: Unclassified-Mixed -- Chapter 9: Nocturnal -- Section 4 Human Partial -- Chapter 10: Simple Partial.-Chapter 11: Simple complex -- Section 5 Human Generalized -- Chapter 12: Tonic Clonic -- Chapter 13: Tonic -- Chapter 14: Atonic -- Chapter 15: Myoconic -- Chapter 16: Absence -- Section 6 Human -- Chapter 17: Unclassified-Mixed -- Chapter 18: Nocturnal -- Section 7 Miscellaneous -- Chapter 19: Pediatric Considerations -- Chapter 20 : Surgery -- Chapter 21: Status Epilepticus -- Chapter 22: Epilogue. 
520 |a Correlation is a vital element in epilepsy research, especially given the condition’s notorious resistance to treatment. With a current ‘rate of translation’ estimated at between seven and nine years, and a translation ‘success rate’ of below 50 per cent, there is room for improvement in the correlative research exploring this intractable condition. Epilepsy: Animal and Human Correlations offers judiciously selected material with clear correlative relevance. Arranged according to animal studies and related studies in the human population, each chapter covers clinical description, neurophysiology, neurochemistry, neuropathology, and treatment attempts. The human chapters have an additional section detailing studies based on counterpart animal studies, as well as covering promising further research suggested by animal results. The book includes a clear statement of the rationale for future human clinical investigations based on animal results. The chapters cover animal and human studies related to both simple and complex partial seizures. It covers typical as well as atypical seizures, and includes material on some seizure disorders which resist neat classification. Studies conducted in the primate population receive careful attention     About the Author: The work of Dr. David W. McCandless spanned over 35 years of laboratory research into basic mechanisms of various metabolic encepha lopathies. He was the Fo unding Editor of the journal Metabolic Brain Disease (Springer), now in its 27th year. Dr. McCandless served on the faculty or research staff at The University of Vermont College of Medicine, NIH-NINCDS, University of Texas Medical School at Houston, and The Chicago Medical School, and was a visiting professor at Washington University School of Medicine. Most recently, he served as the John J. Sheinin Professor of Anatomy in the Department of Cell Biology and Anatomy at The Chicago Medical School, Rosalind Franklin University, North Chicago, IL, USA.     About the Author: The work of Dr. David W. McCandless spanned over 35 years of laboratory research into basic mechanisms of various metabolic encephalopathies. He was the Founding Editor of the journal Metabolic Brain Disease (Springer), now in its 27th year. Dr. McCandless served on the faculty or research staff at The University of Vermont College of Medicine, NIH-NINCDS, University of Texas Medical School at Houston, and The Chicago Medical School, and was a visiting professor at Washington University School of Medicine. Most recently, he served as the John J. Sheinin Professor of Anatomy in the Department of Cell Biology and Anatomy at The Chicago Medical School, Rosalind Franklin University, North Chicago, IL, USA. About the Author: The work of Dr. David W. McCandless spanne d over 35 years of laboratory research into basic mechan isms of various metabolic encephalopathies. He was the Founding Editor of the journal Metabolic Brain Disease (Springer), now in its 27th year. Dr. McCandless served on the faculty or research staff at The University of Vermont College of Medicine, NIH-NINCDS, University of Texas Medical School at Houston, and The Chicago Medical School, and was a visiting professor at Washington University School of Medicine. Most recently, he served as the John J. Sheinin Professor of Anatomy in the Department of Cell Biology and Anatomy at The Chicago Medical School, Rosalind Franklin University, North Chicago, IL, USA.     About the Author: The work of Dr. David W. McCandless spanned over 35 years of laboratory research into basic mechanisms of various metabolic encephalopathies. He was the Founding Editor of the journal Metabolic Brain Disease (Springer), now in its 27th year. Dr. McCandless served on the faculty or research staff at The University of Vermont College of Medicine, NIH-NINCDS, University of Texas Medical School at Houston, and The Chicago Medical School, and was a visiting professor at Washington University School of Medicine. Most recently, he served as the John J. Sheinin Professor of Anatomy in the Department of Cell Biology and Anatomy at The Chicago Medical School, Rosalind Franklin University, North Chicago, IL, USA. About the Author: The work of Dr. David W. McCandless spanned o ver 35 years of laboratory research into basic mechanisms of various metabolic encephalopathies. He was the Founding Editor of the journal Metabolic Brain Disease (Springer), now in its 27th year. Dr. McCandless served on the faculty or research staff at The University of Vermont College of Medicine, NIH-NINCDS, University of Texas Medical School at Houston, and The Chicago Medical School, and was a visiting professor at Washington University School of Medicine. Most recently, he served as the John J. Sheinin Professor of Anatomy in the Department of Cell Biology and Anatomy at The Chicago Medical School, Rosalind Franklin University, North Chicago, IL, USA. Epilepsy: Animal and Human Correlations offers judiciously selected material with clear correlative relevance. Arranged according to animal studies and related studies in the human population, each chapter covers clinical description, neurophysiology, neurochemistry, neuropathology, and treatment attempts. The human chapters have an additional section detailing studies based on counterpart animal studies, as well as covering promising further research suggested by animal results. The book includes a clear statement of the rationale for future human clinical investigations based on animal results. The chapters cover animal and human studies related to both simple and complex partial s eizures. It covers typical as well as atypical seizures, and includes material on some seizure diso rders which resist neat classification. Studies conducted in the primate population receive careful attention     About the Author: The work of Dr. David W. McCandless spanned over 35 years of laboratory research into basic mechanisms of various metabolic encephalopathies. He was the Founding Editor of the journal Metabolic Brain Disease (Springer), now in its 27th year. Dr. McCandless served on the faculty or research staff at The University of Vermont College of Medicine, NIH-NINCDS, University of Texas Medical School at Houston, and The Chicago Medical School, and was a visiting professor at Washington University School of Medicine. Most recently, he served as the John J. Sheinin Professor of Anatomy in the Department of Cell Biology and Anatomy at The Chicago Medical School, Rosalind Franklin University, North Chicago, IL, USA.     About the Author: The work of Dr. David W. McCandless spanned over 35 years of laboratory research into basic mechanisms of various metabolic encephalopathies. He was the Founding Editor of the journal Metabolic Brain Disease (Springer), now in its 27th year. Dr. McCandless served on the faculty or research staff at The University of Vermont College of Medicine, NIH-NINCDS, University of Texas Medica l School at Houston, and The Chicago Medical School, and was a visiting professor at Washington University School of Medicine. Most recently , he served as the John J. Sheinin Professor of Anatomy in the Department of Cell Biology and Anatomy at The Chicago Medical School, Rosalind Franklin University, North Chicago, IL, USA. About the Author: The work of Dr. David W. McCandless spanned over 35 years of laboratory research into basic mechanisms of various metabolic encephalopathies. He was the Founding Editor of the journal Metabolic Brain Disease (Springer), now in its 27th year. Dr. McCandless served on the faculty or research staff at The University of Vermont College of Medicine, NIH-NINCDS, University of Texas Medical School at Houston, and The Chicago Medical School, and was a visiting professor at Washington University School of Medicine. Most recently, he served as the John J.  
520 |a Sheinin Professor of Anatomy in the Department of Cell Biology and Anatomy at The Chicago Medical School, Rosalind Franklin University, North Chicago, IL, USA. The chapters cover animal and human studies related to both simple and complex partial seizures. It covers typical as well as atypical seizures, and includes material on some seizure disorders which resist neat classification. Studies conducted in the primate population receive careful attention     About the Author: The work of Dr. David W. McCandless spanned over 35 years of laboratory research into basic mechanisms of various metabolic encephalopathies. He was the Founding Editor of t he journal Metabolic Brain Disease (Springer), now in its 27th year. Dr. McCandless served on the faculty or research staff at The University of Vermont College of Medicine, NIH-NINCDS, University of Texas Medical School at Houston, and The Chicago Medical School, and was a visiting professor at Washington University School of Medicine. Most recently, he served as the John J. Sheinin Professor of Anatomy in the Department of Cell Biology and Anatomy at The Chicago Medical School, Rosalind Franklin University, North Chicago, IL, USA.     About the Author: The work of Dr. David W. McCandless spanned over 35 years of laboratory research into basic mechanisms of various metabolic encephalopathies. He was the Founding Editor of the journal Metabolic Brain Disease (Springer), now in its 27th year. Dr. McCandless served on the faculty or research staff at The University of Vermont College of Medicine, NIH-NINCDS, University of Texas Medical School at Houston, and The Chicago Medical School, and was a visiting professor at Washington University School of Medicine. Most recently, he served as the John J. Sheinin Professor of Anatomy in the Department of Cell Biology and Anatomy at The Chicago Medical School, Rosalind Frankl in University, North Chicago, IL, USA. About the Author: The work of Dr. David W. McCandless spanned over 35 years of laboratory research into basic mechanisms of various me tabolic encephalopathies. He was the Foun. 
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