Insulin-like Growth Factors and Cancer From Basic Biology to Therapeutics /

The insulin-like growth factor system has been shown to play a critical role in cancer development and progression. Insulin-like Growth Factors and Cancer: From Basic Biology to Therapeutics, specifically brings these aspects to the reader. The volume covers the epidemiological aspects of the relati...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: LeRoith, Derek (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Boston, MA : Springer US, 2012.
Σειρά:Cancer Drug Discovery and Development
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Preface
  • Epidemiology of IGF-1 and Cancer
  • Aging and Cancer: The IGF-I Connection
  • Obesity, Type 2 Diabetes and Cancer
  • IGF System and Breast Cancer
  • The Role of Insulin-Like Growth Factor Signaling in Prostate Cancer Development and Progression
  • Mouse Models of IGF-1 Deficiency
  • Insulin-like Growth Factor Signaling in Pediatric Sarcomas
  • Cancer Genes, Tumor Suppressors, and Regulation of IGF-1R Expression in Cancer
  • Mouse Models of IGF-1R and Cancer
  • Targeting the Insulin-Like Growth Factor-I Receptor in Cancer Therapy
  • Targeting Insulin-like Growth Factor (IGF-1R) and Insulin Receptor Signaling by Tyrosine Kinase Inhibitors in Cancer
  • Calories and Cancer:  The Role of Insulin-like Growth Factor
  • Cancer Cell Metabolism
  • Overlaps between the Insulin and IGF-1R and Cancer
  • Index.