Fuzziness Structural Disorder in Protein Complexes /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Fuxreiter, Monika (Επιμελητής έκδοσης), Tompa, Peter (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer US, 2012.
• Σειρά: Advances in Experimental Medicine and Biology, 725
• Θέματα: Medicine.; Molecular biology.; Biomedicine.; Biomedicine general.; Molecular Medicine.

Detailed characterization of fuzzy interactions will be of central importance for understanding the diverse biological functions of intrinsically disordered proteins in complex eukaryotic signaling networks. In this volume, Peter Tompa and Monika Fuxreiter have assembled a series of papers that addr...

Πίνακας περιεχομένων:

• Fuzzy Complexes: A More Stochastic View of Protein Function
• Dynamic Fuzziness During Linker Histone Action
• Protein Flexibility in Regulation of Cell Proliferation: Advantages for Signaling and Opportunities for Novel Therapeutics
• Interplay Between Protein Order, Disorder and Oligomericity in Receptor Signaling
• Consequences of Fuzziness in the NFkB/IkBa Interaction
• Roles for Intrinsic Disorder and Fuzziness in Generating Context‑ Specific Function in Ultrabithorax, a Hox Transcription Factor
• Molecular Recognition by the EWS Transcriptional Activation Domain
• The Measles Virus Ntail‑Xd Complex: An Illustrative Example of Fuzziness
• Fuzziness in the Core of the Human Pathogenic Viruses HCV and HIV
• Structural Disorder and Protein Elasticity
• “Fuzziness” in the Cellular Interactome: A Historical Perspective.