Tumour-Associated Macrophages

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Lawrence, Toby (Επιμελητής έκδοσης), Hagemann, Thorsten (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York, 2012.
• Θέματα: Medicine.; Cancer research.; Pharmacology.; Biomedicine.; Cancer Research.; Pharmacology/Toxicology.

Macrophages are tissue resident phagocytes that have important roles in development and immunity. The observation that cancers become infiltrated by large numbers of macrophages was first made by Virchow in 1863, clinical and experimental studies suggest tumor-associated macrophages (TAM) are critic...

Πίνακας περιεχομένων:

• Preface
• Macrophage Phenotype in Tumors
• Role of Tumour-Associated Macrophages in the Regulation of Tumour Angiogenesis
• The Role of Tumor-Associated Macrophages in Malignant Invasion
• Tumor-Induced Immune Suppression by Myeloid Cells
• TAM: A Moving Clinical Target
• Arginine Metanolism and Tumour Associated Macrophages
• Indoleamine 2,3-dioxygenaseAmino acid metabolism and tumor-associated macrophages: regulation in cancer-associated inflammation and immune escape
• Vascular Endothelial Growth Factor and Tumor-associated macrophages
• TLR Signaling and Tumor-associated Macrophages
• SHIP and Tumor-Associated Macrophages
• NF-KappaB-Mediated Regulation of Tumor-Associated Macrophages: Mechanisms and Signifance
• Role of hypoxia-inducible transcription factors HIF-a for TAM function
• Index.        .