Formulating Poorly Water Soluble Drugs

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Williams III, Robert O. (Επιμελητής έκδοσης), Watts, Alan B. (Επιμελητής έκδοσης), Miller, Dave A. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York, 2012.
• Έκδοση: 1.
• Σειρά: AAPS Advances in the Pharmaceutical Sciences Series, 3
• Θέματα: Medicine.; Pharmaceutical technology.; Biomedicine.; Pharmaceutical Sciences/Technology.

A pharmaceutical scientist’s approach toward solubility enhancement of a poorly water-soluble molecule typically includes detailed characterization of the compound’s physiochemical properties, solid-state modifications, advanced formulation design, non-conventional process technologies, advanced ana...

Πίνακας περιεχομένων:

• Route-Specific Challenges in Delivery of Poorly Water Soluble Drugs
• Optimizing the Formulation of Poorly Water Soluble Drugs
• Solid-State Techniques for Improving Solubility
• Mechanical Particle Size Reduction Techniques
• Solubilized Formulations
• Injectable Formulations of Poorly Water Soluble Drugs
• Design and Development of Self-Emulsifying Lipid Formulations for Improving Oral Bioavailability of Poorly Water-Soluble and Lipophilic Drugs
• Structured Development Approach for Amorphous Systems
• Melt Extrusion
• Spray Drying Technology
• Pharmaceutical Cryogenic Technologies
• Precipitation Technologies for Nanoparticle Production
• Emerging Technologies to Increase the Bioavailability of Poorly Water Soluble Drugs
• Regulatory Considerations for Development and Commercialization of Poorly Water Soluble Drugs.