Signaling Pathways in Cancer Pathogenesis and Therapy

• Corporate Author: SpringerLink (Online service)
• Other Authors: Frank, David A. (Editor)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York, 2012.
• Subjects: Medicine.; Cancer research.; Pharmacology.; Biomedicine.; Cancer Research.; Pharmacology/Toxicology.

Since the 1940s, the treatment of advanced cancer has been based on administering maximal doses of non-specifically toxic drugs in the hope that cancer cells would be killed more effectively than normal cells.  While this is occasionally successful, for most common cancers only a minority of patient...

Table of Contents:

• Signaling Pathways in Cancer:  21st Century Approaches to Cancer Therapy
• Current And Next Generation Antimitotic Therapies In Cancer
• DNA Damage Checkpoint Signaling Pathways in Human Cancer
• Non-Receptor Tyrosine Kinases and their Roles in Cancer
• The Hedgehog Signaling Pathway in Cancer Pathogenesis and Therapy
• Wnt Signaling in Cancer Pathogenesis and Therapeutics
• STAT Signaling in the Pathogenesis and Treatment of Cancer
• Protein Therapeutics in Oncology.- Index   .