Caveolins and Caveolae Roles in Signaling and Disease Mechanisms /

• Corporate Author: SpringerLink (Online service)
• Other Authors: Jasmin, Jean-François (Editor), Frank, Philippe G. (Editor), Lisanti, Michael P. (Editor)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer US, 2012.
• Series: Advances in Experimental Medicine and Biology, 729
• Subjects: Medicine.; Biomedicine.; Biomedicine general.

Caveolae are 50-100 nm flask-shaped invaginations of the plasma membrane that are primarily composed of cholesterol and sphingolipids. Using modern electron microscopy techniques, caveolae can be observed as omega-shaped invaginations of the plasma membrane, fully-invaginated caveolae, grape-like cl...

Table of Contents:

• Lipid Rafts, Caveolae and GPI‑Linked Proteins
• Caveolae and the Regulation of Endocytosis
• Caveolin‑1: Role in Cell Signaling
• Regulation of eNOS in Caveolae
• Recent Developments in the Interactions Between Caveolin and Pathogens
• Caveolin‑1 and Breast Cancer: A New Clinical Perspective
• Caveolin‑1 and Prostate Cancer Progression
• Caveolins and Caveolae, Roles in Insulin Signalling and Diabetes
• Atherosclerosis, Caveolae and Caveolin‑1
• Caveolins and Heart Diseases
•  Caveolins and Lung Function.