Protein Dimerization and Oligomerization in Biology

• Corporate Author: SpringerLink (Online service)
• Other Authors: Matthews, Jacqueline M. (Editor)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York : Imprint: Springer, 2012.
• Series: Advances in Experimental Medicine and Biology, 747
• Subjects: Medicine.; Molecular biology.; Biomedicine.; Biomedicine general.; Molecular Medicine.

This volume has a strong focus on homo-oligomerization, which is surprisingly common. However, protein function is so often linked to both homo- and hetero-oligomerization and many heterologous interactions likely evolved from homologous interaction, so this volume also covers many aspects of hetero...

Table of Contents:

• Dimers, Oligomers, Everywhere
• The Detection and Quantitation of Protein Oligomerization
• Computational and Structural Characterisation of Protein Associations
• Death by Caspase Dimerization
• The Relationship between Oligomeric State and Protein Function
• Oligonucleotide Binding Proteins: The Occurrence of Dimer and Multimer Formation
• Homo‑ and Heterodimerization in Transcriptional Regulation
• OligomeriZation at the Membrane: Potassium Channel Structure and Function
• Implications of 3D Domain Swapping for Protein Folding, Misfolding and Function
• From artificial antibodies to nanosprings: The biophysical properties of repeat proteins.