Systems Biology of Parkinson's Disease

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Wellstead, Peter (Επιμελητής έκδοσης), Cloutier, Mathieu (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York, 2012.
• Θέματα: Life sciences.; Neurosciences.; Systems biology.; Life Sciences.; Systems Biology.; Biomedicine general.

This text is the first to present a study of Parkinson’s disease from a Systems Biology perspective. By placing the condition at centre stage, the authors have been able to provide a wide ranging modelling and systems analysis that is focussed on a multi-facetted and highly complex condition. The bo...

Πίνακας περιεχομένων:

• Imaging of dopaminergic neurons and the implications for Parkinson’s disease
• Modelling and simulation of brain energy metabolism: energy and Parkinson's disease
• Systems Biology of Aging: Opportunities for Parkinson’s Disease
• Mitochondrion- and Endoplasmic Reticulum-Induced SK Channel Dysregulation as a Potential Origin of the Selective Neurodegeneration in Parkinson’s Disease
• Energetics of Ion Transport in Dopaminergic Substantia nigra Neurons: ion exchange dynamics at the pacemaking membrane
• Real-time In Vivo Sensing of Neurochemicals
• Modeling protein and oxidative metabolism in Parkinson's disease
• Mathematical Models of Dopamine Metabolism in Parkinson’s Disease
• Index.