LC-MS in Drug Bioanalysis
High performance liquid chromatography – mass spectrometry (LC-MS) combines the separation power of liquid chromatography with the high sensitivity and selectivity of mass spectrometry. Therefore, LC-MS becomes the method of choice for drug bioanalysis in therapeutic drug monitoring, tox...
| Συγγραφή απο Οργανισμό/Αρχή: | |
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| Άλλοι συγγραφείς: | , |
| Μορφή: | Ηλεκτρονική πηγή Ηλ. βιβλίο |
| Γλώσσα: | English |
| Έκδοση: |
Boston, MA :
Springer US : Imprint: Springer,
2012.
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| Θέματα: | |
| Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- Internal standards for quantitative LC-MS bioanalysis
- Method development, validation and sample analysis for regulated quantitative bioanalysis using LC-MS/MS
- Impact of sampling paper/cards on bioanalytical quantitation via dried blood spots by liquid chromatography - mass spectrometry
- Highly sensitive pharmaceutical and clinical analysis using selective solid-phase extraction coupled to microflow liquid chromatography and isotope-dilution mass spectrometry
- Pitfalls of LC-MS/MS in the clinical laboratory
- Therapeutic drug monitoring to support clinical pharmacogenomics
- Liquid chromatography - mass spectrometry for the determination of antidepressants and some of their major metabolites in human biological matrices
- The analysis of antipsychotic drugs in human biosamples by LC-MS
- Therapeutic drug monitoring of targeted anticancer therapy - tyrosine kinase inhibitors and selective oestrogen receptor modulators: a clinical pharmacology laboratory perspective
- Applications of mass spectrometry in analyses of steroid hormones
- Liquid chromatography - mass spectrometric analysis of tropane alkaloids in mammalian samples: techniques and applications
- Analysis of illicit drugs in human biological samples by LC-MSn
- Use of matrix assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) in the development of novel small molecule drugs
- A planar integrated micro mass spectrometer.
