Cancer Immunotherapy Paradigms, Practice and Promise /

This volume is a comprehensive discussion of the major factors affecting tumor immunology and a discussion of all major anti-cancer immunotherapeutic agents approved by the Food and Drug Administration of the United States and by European agencies. Many promising but unapproved agents in clinical tr...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Curiel, Tyler J. (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2013.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Introduction
  • Historical Perspectives and Current Trends in Cancer Immunotherapy
  • T cell and Antigen-Presenting Cell Subsets in the Tumor Microenvironment
  • Adoptive T Cell Transfer
  • Dendritic Cell-Based Cancer Immunotherapy: Achievements and novel concepts
  • Peptide and Protein-based Cancer Vaccines
  • Antigen Targeting to Dendritic Cells for Cancer Immunotherapy
  • Cytokines in the Treatment of Cancer
  • Immune Co-signaling to Treat Cance
  • Managing Regulatory T cells
  • Myeloid-Derived Suppressor Cells in Cancer: Mechanisms and therapeutic perspectives
  • Antibodies as Cancer Immunotherapy
  • Targeted Toxins in Cancer Immunotherapy
  • Miscellaneous Approaches and Considerations: TLR agonists and other inflammatory agents, anti-chemokine agents, infectious agents, tumor stroma targeting, age and sex effects, and miscellaneous small molecules
  • Issues in Pre-clinical Models, Clinical Trial Design and Analytical Considerations in Developing and Evaluating Novel Cancer Immunotherapies
  • Monitoring Antigen-Specific Responses in Clinical Trials of Immunotherapy
  • Index.