Microdialysis in Drug Development
In vivo target site concentrations are probably the most important determinant of drug effects. Traditionally, linking drug concentrations to drug effects has been accomplished by modelling blood-derived data, mostly because a direct quantification of tissue concentrations has been beyond technical...
| Συγγραφή απο Οργανισμό/Αρχή: | |
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| Άλλοι συγγραφείς: | |
| Μορφή: | Ηλεκτρονική πηγή Ηλ. βιβλίο |
| Γλώσσα: | English |
| Έκδοση: |
New York, NY :
Springer New York : Imprint: Springer,
2013.
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| Σειρά: | AAPS Advances in the Pharmaceutical Sciences Series,
4 |
| Θέματα: | |
| Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- Introduction to the Microdialysis Technology
- Recovery and Calibration Techniques: Toward Quantitative Microdialysis
- Analytical Considerations for Microdialysis Sampling
- Regulatory Aspects of Microdialysis: A United States Food & Drug Administration Perspective
- Microdialysis in CNS PKPD Research: Unraveling Unbound Concentrations
- Microdialysis in Antibiotic Research
- Skin and Transdermal Drug Delivery: Advantages and Challenges
- Translational Approaches For Predicting CNS Drug Effects Using Microdialysis
- Extracellular Amyloid-β Protein Dynamics in Alzheimer's Disease
- Microdialysis in Pain Research
- Microdialysis in Ocular Drug Development
- Microdialysis in Metabolic Research
- High Molecular Weight Targets and Treatments Using Microdialysis
- Complementary Techniques – Positron Emission Tomography
- Open Flow Microperfusion: An Alternative Method to Microdialysis?
- Microdialysis in Internal Organs and Tumors.
