Prions and Diseases Volume 1, Physiology and Pathophysiology /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Zou, Wen-Quan (Επιμελητής έκδοσης), Gambetti, Pierluigi (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2013.
• Θέματα: Medicine.; Human physiology.; Neurosciences.; Neurology.; Biochemistry.; Proteins.; Animal physiology.; Biomedicine.; Human Physiology.; Protein Science.; Animal Physiology.; Biochemistry, general.

Transmissible spongiform encephalopathies (TSE), now broadly known as prion diseases, have been recognized for nearly 300 years in animals and almost 100 years in humans. However, the nature of the transmissible agent had largely remained a mystery until Stanley Prusiner discovered the infectious is...

Πίνακας περιεχομένων:

• Transmissible Spongiform Encephalopathy: from the High Middle Ages to Daniel Carlton Gajdusek
• The Rich Chemistry of the Copper and Zinc Sites in Cellular Prion Protein
• Role of Cellular Prion Protein in the Amyloid-ß Oligomer Pathophysiology of Alzheimer’s Disease
• Cellular Prion Protein and Cancers
• Insoluble Cellular Prion Protein
• Protein Misfolding Cyclic Amplification
• Cofactor Involvement in Prion Propagation
• Prion Protein Conversion and Lipids
• New Perspectives on Prion Conversion: Introducing a Mechanism of Deformed Templating
• Infectious and Pathogenic Forms of Prion Protein
• Cellular Mechanisms of Propagation and Clearance
• Molecular Mechanisms Encoding Quantitative and Qualitative Traits of Prion Strains
• Modeling the Cell Biology of Prions
• Prion Strain Interference
• Introduction to Yeast and Fungal Prions
• Yeast Prions are Pathogenic, in-register Parallel Amyloids.