The Pathogenic Spirochetes: strategies for evasion of host immunity and persistence

• Corporate Author: SpringerLink (Online service)
• Other Authors: Embers, Monica E. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Boston, MA : Springer US : Imprint: Springer, 2012.
• Subjects: Medicine.; Immunology.; Antibodies.; Medical microbiology.; Biomedicine.; Medical Microbiology.

This book explores the many mechanisms by which the most prevalent Spirochetal pathogens persist in a healthy immune-competent host. Among them are the direct and indirect suppression of host immune signals, phase and antigenic variation, escaping recognition by host complement proteins, and seclusi...

Table of Contents:

• Treponema pallidum
• Immunoseclusion and Chronic Infection
• Treponema Denticola
• Borrelial Complement-binding Proteins
• Treponema Pallidum Repeat (tpr) Genes and Antigenic Variation
• Antigenic Variation of V1sE by Borrelia Burgdorferi
• Modulation of Cytokine Signaling by Borrelia Burgdorferi
• Leptospira: Invasion, Pathogenesis and Persistence
• Immune Resistance by Relapsing  Fever Spirochetes
• Neuroborreliosis Caused by Borrelia Burgdorferi: Possible Role of Glial Cells
• Antibiotic Resistance in Treponema Pallidum subsp. Pallidum, the Syphilis Agent
• Borrelia Burgdorferi Persistence Post-Antibiotic Treatment.