Pathobiology of Cancer Regimen-Related Toxicities

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Sonis, Stephen T. (Επιμελητής έκδοσης), Keefe, Dorothy M. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2013.
• Θέματα: Medicine.; Cancer research.; Pharmacology.; Biomedicine.; Cancer Research.; Pharmacology/Toxicology.

Toxicities have been consistent undesirable companions of every form of radiation and drug cancer treatment regimens.  In addition to the potential for toxicities to devastate patients’ quality of life, they generate huge incremental financial costs, and sap patients’ ability to tolerate definitive...

Πίνακας περιεχομένων:

• Preface.-Epidemiology and outcomes of regimen-related toxicities
• The biological basis for differences in normal tissue response to radiation therapy and strategies to establish predictive assays for individual complication risk
• The bystander effect: Ionizing radiation-induced non-targeted effects: Evidence, mechanism and significance
• The role of genes on the metabolism of chemotherapeutic agents and their impact on toxicity.-  Animal models of regimen-related toxicities
• Nausea and Vomiting
• Mucositis
• Dermatitis and Alopecia.-  Fibrosis.-  Myelosuppression
• Neuropathy
• Fatigue
• Xerostomia
• Osteonecrosis
• Conclusions and therapeutic opportunities
• Index.