Kisspeptin Signaling in Reproductive Biology

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Kauffman, Alexander S. (Επιμελητής έκδοσης), Smith, Jeremy T. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2013.
• Σειρά: Advances in Experimental Medicine and Biology, 784
• Θέματα: Medicine.; Neurosciences.; Endocrinology.; Reproductive medicine.; Biomedicine.; Biomedicine general.; Reproductive Medicine.

Kisspeptin has been shown to be both necessary and sufficient for activation of the reproductive axis, during puberty and later in adulthood.  This makes kisspeptin a fundamental component of the reproductive axis. Kisspeptin has been deemed the single most potent stimulator of GnRH neurons yet know...

Πίνακας περιεχομένων:

• Part One: Kisspeptin Signaling in vivo and in vitro
• Kisspeptin: Past, Present and Prologue
• Structure, Synthesis, and Phylogeny of Kisspeptin and its Receptor
• Neuroanatomy of the Kisspeptin Signaling System in Mammals: Comparative and Developmental Aspects
• The Effects of Kisspeptin on Gonadotropin Release in Non-Human Mammals
• Effects of Kisspeptin on Hormone Secretion in Humans
• Kisspeptin Excitation of GnRH Neurons
• Molecular Biology of the Kisspeptin Receptor: Signaling, Function, and Mutations
• Kisspeptin Antagonists
• Kisspeptin and Clinical Disorders
• Beyond the GnRH Axis: Kisspeptin Regulation of the Oxytocin System in Pregnancy and Lactation
• Part Two: Development and Regulation of Kisspeptin Neurons
• The Development of Kisspeptin Circuits in the Mammalian Brain
• Kisspeptin and Puberty in Mammals
• Sex Steroid Regulation of Kisspeptin Circuits
• Kisspeptin and GnRH Pulse Generation
• Interactions between Kisspeptins and Neurokinin B
• Electrophysiology of Kisspeptin Neurons
• Metabolic Regulation of Kisspeptin
• Circadian Regulation of Kisspeptin in Female Reproductive Functioning
• Kisspeptin and Seasonality of Reproduction
• Stress Regulation of Kisspeptin in the Modulation of Reproductive Function
• Effects of Environmental Endocrine Disruptors and Phytoestrogens on the Kisspeptin System
• Model Systems for Studying Kisspeptin Signaling: Mice and Cells
• Index.