Prostate Cancer Biochemistry, Molecular Biology and Genetics /

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Tindall, Donald J. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2013.
• Σειρά: Protein Reviews ; 16
• Θέματα: Medicine.; Cancer research.; Medical biochemistry.; Proteins.; Cell biology.; Systems biology.; Biological systems.; Biomedicine.; Cancer Research.; Medical Biochemistry.; Cell Biology.; Protein Science.; Receptors.; Biological Networks, Systems Biology.

Prostate cancer is the most frequently diagnosed non-cutaneous malignancy in men, and the second leading cause of male cancer-related mortality in the United States.  The last decade has seen unprecedented progress in the detection, prognosis, treatment and prevention of prostate cancer. These advan...

Πίνακας περιεχομένων:

• Preface
• Section 1: Cell Biology
• Stem Cells in the Normal and Malignant Prostate
• Role of Reactive Stroma in Prostate Cancer
• The Role of Cholesterol in Prostate Cancer
• Section 2: Genetics: PTEN in Prostate Cancer
• ETS fusion genes in prostate cancer
• Section 3: Cell Signaling
• Signaling Mechanisms of Vav3, a Guanine Nucleotide Exchange Factor and Androgen Receptor Coactivator, in Physiology and Prostate Cancer Progression
• Transforming Growth Factor-beta (TGF-b) in Prostate Cancer
• The p38 MAPK Pathway in Prostate Cancer
• NF-kappaB2/p52 in Prostate Cancer
• The functional role of DAB2IP, a homeostatic factor, in prostate cancer
• Tyrosine Kinases in Prostate Cancer
• Human prostatic acid phosphatase in prostate carcinogenesis
• Section 4: Hormonal
• Truncated Androgen Receptor Splice Variants in Prostate Cancer
• Biology and Clinical Relevance of Estrogen Receptors in Prostate Cancer
• Vitamin D and Prostate Cancer
• HDAC6 regulation of androgen signaling in prostate cancer
• Beyond the cell cycle: Implications of D-type cyclin deregulation in Pca
• Section 5: Cell Death
• Role of Par- in Prostate Cancer
• Autophagy and Prostate Cancer Therapeutics
• Index.