Molecular Mechanisms of Tumor Cell Resistance to Chemotherapy Targeted Therapies to Reverse Resistance /

Patients with various cancers are treated with conventional chemotherapeutic drugs and the majority responds well to such therapies. However, there is a subset of patients who does not respond initially and another subset who no longer responds to further treatments. Clearly, in those two subsets of...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
Άλλοι συγγραφείς: Bonavida, Benjamin (Επιμελητής έκδοσης)
Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2013.
Σειρά:Resistance to Targeted Anti-Cancer Therapeutics, 1
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Preface
  • Multidrug resistance in cancer: a tale of ABC drug transporters
  • Multidrug resistance: a role for membrane physics, pH and drug transporters
  • Mechanisms and potential therapies for acquired resistance to inhibitors targeting the Raf or MEK kinases in cancer
  • Mechanisms of resistance to targeted B-Raf therapies
  • Role of β1integrins in the complication and drug resistance against lung cancer: targeting β1integrins to eradicate lung cancer
  • Aldo-keto reductases as new therapeutic targets for colon cancer chemoresistance
  • Overcoming drug resistance through elevation of ROS in cancer
  • Cancer stem cells in resistance to cytotoxic drugs: implications in chemotherapy
  • Two birds with a stone: molecular cancer therapy targeting signal transduction and DNA repair pathways
  • Collateral sensitivity in drug-resistant tumor cells
  • Human cancer resistance to trail-apoptotic pathway-targeted therapies
  • The dark side of apoptosis
  • Index.