Cholesterol and Presynaptic Glutamate Transport in the Brain

• Κύριος συγγραφέας: Borisova, Tatiana (Συγγραφέας)
• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2013.
• Σειρά: SpringerBriefs in Neuroscience, 12
• Θέματα: Medicine.; Neurosciences.; Neurochemistry.; Biomedicine.

Glutamate is the primary excitatory neurotransmitter in the CNS and disturbances in glutamate transport contribute to a number of neurological and neurodegenerative disorders.  Appropriate levels of cholesterol are very important for the proper functioning of glutamate transport while unbalanced lev...

Πίνακας περιεχομένων:

• Presynaptic glutamate transport in the brain
• Cholesterol and its role in synaptic transmission
• Effects of cholesterol-depleting agent methyl-b-cyclodextrin (MbCD) on the functional state of brain nerve terminals
• The extracellular level and uptake of glutamate in cholesterol-deficient nerve terminals
• Unstimulated and exocytotic glutamate release from cholesterol-deficient nerve terminals
• Neuroprotection by lowering cholesterol.