Protein Tyrosine Phosphatase Control of Metabolism

• Συγγραφή απο Οργανισμό/Αρχή: SpringerLink (Online service)
• Άλλοι συγγραφείς: Bence, Kendra K. (Επιμελητής έκδοσης)
• Μορφή: Ηλεκτρονική πηγή Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: New York, NY : Springer New York : Imprint: Springer, 2013.
• Θέματα: Life sciences.; Endocrinology.; Biochemistry.; Proteins.; Life Sciences.; Protein Science.; Biochemistry, general.; Biomedicine general.

Tyrosine phosphorylation is a rapid and reversible protein modification catalyzed by the yin and yang activities of protein tyrosine kinases (PTKs) and protein tyrosine phosphatases (PTPs).  A multitude of PTPs have been implicated in human disease, with a growing number of PTPs now known to play ma...

Πίνακας περιεχομένων:

• Redox Regulation of PTPs in Metabolism: Focus on Assays
• Quantitative Modeling of PTPs and Implications for Studying Metabolic Signaling
• Protein-Tyrosine Phosphatase 1B Substrates and Control of Metabolism
• PTP1B and TCPTP in CNS Signaling and Energy Balance
• PTP1B in the Periphery: Regulating Insulin Sensitivity and ER Stress
• Role of Protein Tyrosine Phosphatase 1B in Hepatocyte-Specific Insulin and Growth Factor Signaling
• PTP1B in Obesity-Related Cardiovascular Runction
• Role of SHP2 Protein Tyrosine Phosphatase in Cardiac Metabolism
• Metabolic Effects of Neural and Pancreatic SHP2
• Protein Tyrosine Phosphatase Epsilon as a Regulator of Body Weight and Glucose Metabolism
• The Role of LMPTP in the Metabolic Syndrome
• Mitogen-Activated Protein Kinase Phosphatases in Metabolism
• Glycogen Metabolism and Lafora Disease
• Index.