Nuclear Signaling Pathways and Targeting Transcription in Cancer
This book presents the most up-to-date information in the area of targeted therapeutics with a particular focus on pathway-centered approaches and transcription by leading authorities in molecular cancer research. The goal is to cover several critical principles of cancer therapeutics, ranging from...
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| Format: | Electronic eBook |
| Language: | English |
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New York, NY :
Springer New York : Imprint: Humana Press,
2014.
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| Series: | Cancer Drug Discovery and Development,
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| Online Access: | Full Text via HEAL-Link |
Table of Contents:
- Preface
- Steroid Receptor Coactivators (SRCs) as Integrators of Multiple Signaling Pathways in Cancer Progression
- Role of Alteration/Deficiency in Activation (ADA) Complex in the Cell Cycle, Genomic Instability and Cancer
- RUNX2 Transcriptional Regulation in Development and Disease
- Epigenetic Mechanisms of Cancer Metastasis
- Regulatory Effects of Arsenic on Cellular Signaling Pathways: Biological Effects and Therapeutic Implications
- Nuclear Factors Linking Cancer and Inflammation
- Regulation of the Jak/STATs Pathways by Histone Deacetylases
- Receptor Tyrosine Kinases in the Nucleus: Nuclear Functions and Therapeutic Implications in Cancers
- Nucleolar Signaling Determines Cell Fate – The RP-Mdm2-p53 Axis Fine-Tunes Cellular Homeostasis
- Transcriptional Regulation of Lipogenesis as a Therapeutic Target for Cancer Treatment
- Selective Inhibition of Acetyl-Lysine Effector Domains of the Bromodomain Family in Oncology
- Domain Specific Targeting of Cancer
- The Potential of Targeting Splicing for Cancer Therapy
- Exploiting Cell Cycle Pathways in Cancer Therapy: New (and Old) Targets and Potential Strategies
- Histone Demethylases in Prostate Cancer
- Therapeutic Significance of Chromatin Remodeling Complexes in Cancer
- Index.
